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Gene: Kalrn (kalirin, RhoGEF kinase) Rattus norvegicus
Symbol: Kalrn
Name: kalirin, RhoGEF kinase
Description: Exhibits enzyme binding activity. Involved in several processes, including NMDA selective glutamate receptor signaling pathway; generation of neurons; and modification of postsynaptic actin cytoskeleton. Localizes to several cellular components, including glutamatergic synapse; neuronal cell body; and postsynaptic density. Orthologous to human KALRN (kalirin RhoGEF kinase); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cyclin B1; Duo; Hapip; huntingtin-associated protein interacting protein (duo); huntingtin-associated protein-interacting protein; kalirin; P-CIP10; PAM COOH-terminal interactor protein 10; serine/threonine kinase with Dbl- and pleckstrin homology domain; serine/threonine-protein kinase with Dbl- and pleckstrin homology domain
Homo sapiens (human) : KALRN (kalirin RhoGEF kinase)  HGNC  Alliance
Mus musculus (house mouse) : Kalrn (kalirin, RhoGEF kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kalrn (kalirin RhoGEF kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : KALRN (kalirin RhoGEF kinase)
Canis lupus familiaris (dog) : KALRN (kalirin RhoGEF kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kalrn (kalirin RhoGEF kinase)
Chlorocebus sabaeus (African green monkey) : KALRN (kalirin RhoGEF kinase)
Heterocephalus glaber (naked mole-rat) : Kalrn (kalirin RhoGEF kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01169,484,293 - 70,025,682 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1169,484,293 - 70,025,633 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01172,575,016 - 73,115,328 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41168,124,348 - 68,611,336 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11168,205,034 - 68,668,925 (+)NCBI
Celera1165,708,953 - 66,248,259 (+)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Kalrn
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621865
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.