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Gene: Dcn (decorin) Mus musculus
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Symbol: Dcn
Name: decorin
Description: Exhibits extracellular matrix binding activity and glycosaminoglycan binding activity. Involved in peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan. Localizes to the collagen-containing extracellular matrix and extracellular space. Used to study Ehlers-Danlos syndrome and congenital stromal corneal dystrophy. Human ortholog(s) of this gene implicated in breast carcinoma; congenital stromal corneal dystrophy; and malignant glioma. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and sensory organ. Orthologous to human DCN (decorin).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bone proteoglycan II; DC; DSPG2; mDcn; PG40; PGII; PGS2; SLRR1B
Orthologs:
Homo sapiens (human) : DCN (decorin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dcn (decorin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dcn (decorin)
Pan paniscus (bonobo/pygmy chimpanzee) : DCN (decorin)
Canis lupus familiaris (dog) : DCN (decorin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dcn (decorin)
Sus scrofa (pig) : DCN (decorin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381097,479,500 - 97,518,163 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371096,942,134 - 96,980,796 (+)NCBIGRCm37mm9NCBIm37
MGSCv361096,912,055 - 96,947,839 (+)NCBImm8
Celera1099,450,242 - 99,488,904 (+)NCBICelera
Cytogenetic Map10 C3NCBI
cM Map1050.27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Dcn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62188
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.