Gene: Dag1 (dystroglycan 1) Rattus norvegicus
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Symbol: Dag1
Name: dystroglycan 1
Description: Exhibits laminin-1 binding activity; involved in several processes, including aging, angiogenesis involved in wound healing, and nervous system development; localizes to several cellular components, including the basolateral plasma membrane, cell-cell adherens junction, and cytoplasm; used to study myocardial infarction; biomarker of muscular atrophy, primary biliary cirrhosis, and type 2 diabetes mellitus; orthologous to human DAG1 (dystroglycan 1); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; cell-extracellular matrix signaling pathway; dilated cardiomyopathy pathway; INTERACTS WITH (RS)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-dystroglycan; beta-dystroglycan; dystroglycan; dystroglycan 1 (dystrophin-associated glycoprotein 1)
Orthologs:
Homo sapiens (human) : DAG1 (dystroglycan 1)  HGNC  Alliance
Mus musculus (house mouse) : Dag1 (dystroglycan 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dag1 (dystroglycan 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DAG1 (dystroglycan 1)
Canis lupus familiaris (dog) : DAG1 (dystroglycan 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dag1 (dystroglycan 1)
Sus scrofa (pig) : DAG1 (dystroglycan 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08116,980,501 - 116,993,182 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08116,334,176 - 116,346,857 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,470,871 - 113,483,433 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18113,492,696 - 113,493,023 (-)NCBI
Celera8108,195,279 - 108,207,962 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dag1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621890
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.