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Gene: Nr1h2 (nuclear receptor subfamily 1, group H, member 2) Mus musculus
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Symbol: Nr1h2
Name: nuclear receptor subfamily 1, group H, member 2
Description: Exhibits DNA binding activity; nuclear receptor activity; and retinoid X receptor binding activity. Predicted to contribute to sequence-specific DNA binding activity. Involved in several processes, including cholesterol homeostasis; positive regulation of transport; and regulation of transcription by RNA polymerase II. Localizes to nucleus. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human NR1H2 (nuclear receptor subfamily 1 group H member 2); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 8-(4-chlorophenylthio)-cAMP.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI194859; liver X receptor beta; LXR; LXR beta; LXRB; LXRbeta; LXRBSV; NER1; nuclear receptor subfamily 1 group H member 2; OR-1; oxysterols receptor LXR-beta; retinoid X receptor-interacting protein No.15; RIP15; ubiquitously-expressed nuclear receptor 2; Unr; Unr2; UR
Orthologs:
Homo sapiens (human) : NR1H2 (nuclear receptor subfamily 1 group H member 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nr1h2 (nuclear receptor subfamily 1, group H, member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr1h2 (nuclear receptor subfamily 1 group H member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NR1H2 (nuclear receptor subfamily 1 group H member 2)
Canis lupus familiaris (dog) : NR1H2 (nuclear receptor subfamily 1 group H member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr1h2 (nuclear receptor subfamily 1 group H member 2)
Sus scrofa (pig) : NR1H2 (nuclear receptor subfamily 1 group H member 2)
Chlorocebus sabaeus (African green monkey) : NR1H2 (nuclear receptor subfamily 1 group H member 2)
Heterocephalus glaber (naked mole-rat) : Nr1h2 (nuclear receptor subfamily 1 group H member 2)
more info ...
Related Pseudogenes: Nr1h2-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl744,549,616 - 44,553,951 (-)EnsemblGRCm38mm10GRCm38
GRCm38744,549,616 - 44,553,968 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37751,805,002 - 51,809,293 (-)NCBIGRCm37mm9NCBIm37
MGSCv36744,417,674 - 44,421,965 (-)NCBImm8
Celera739,999,761 - 40,004,052 (-)NCBICelera
Cytogenetic Map7B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Nr1h2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62199
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-03-31
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.