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Gene: Rab7 (RAB7, member RAS oncogene family) Mus musculus
Symbol: Rab7
Name: RAB7, member RAS oncogene family
Description: Predicted to have several functions, including Rac GTPase binding activity; purine ribonucleoside binding activity; and retromer complex binding activity. Involved in establishment of vesicle localization and lipophagy. Localizes to several cellular components, including bounding membrane of organelle; lipid droplet; and phagophore assembly site membrane. Predicted to colocalize with retromer complex. Is expressed in limb mesenchyme and lung mesenchyme. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2B. Orthologous to human RAB7A (RAB7A, member RAS oncogene family); PARTICIPATES IN autophagy pathway; interleukin-12 signaling pathway; endocytosis pathway; INTERACTS WITH (S)-nicotine; 1,2-dimethylhydrazine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC102153; Rab7a; ras-related protein Rab-7a
Homo sapiens (human) : RAB7A (RAB7A, member RAS oncogene family)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rab7a (RAB7A, member RAS oncogene family)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rab7a (RAB7A, member RAS oncogene family)
Pan paniscus (bonobo/pygmy chimpanzee) : RAB7A (RAB7A, member RAS oncogene family)
Canis lupus familiaris (dog) : RAB7A (RAB7A, member RAS oncogene family)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rab7a (RAB7A, member RAS oncogene family)
Sus scrofa (pig) : RAB7A (RAB7A, member RAS oncogene family)
Chlorocebus sabaeus (African green monkey) : RAB7A (RAB7A, member RAS oncogene family)
Heterocephalus glaber (naked mole-rat) : Rab7a (RAB7A, member RAS oncogene family)
more info ...
Related Pseudogenes: Gm8475   Rab7-ps1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl687,999,106 - 88,045,270 (-)EnsemblGRCm38mm10GRCm38
GRCm38687,999,106 - 88,045,270 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37687,950,429 - 87,963,684 (-)NCBIGRCm37mm9NCBIm37
MGSCv36687,964,764 - 88,010,861 (-)NCBImm8
Celera689,937,361 - 89,950,664 (-)NCBICelera
Cytogenetic Map6D1NCBI
cM Map639.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rab7
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62201
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.