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Gene: Tfpi (tissue factor pathway inhibitor) Mus musculus
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Symbol: Tfpi
Name: tissue factor pathway inhibitor
Description: Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of blood coagulation. Localizes to extracellular space. Is expressed in several structures, including central nervous system; hemolymphoid system; liver; lung; and retina. Human ortholog(s) of this gene implicated in several diseases, including factor VIII deficiency; osteonecrosis; thrombophilia (multiple); toxic shock syndrome; and transient cerebral ischemia. Orthologous to human TFPI (tissue factor pathway inhibitor); PARTICIPATES IN coagulation cascade pathway; syndecan signaling pathway; complement system pathway; INTERACTS WITH 1,2-dichloroethane; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A630013F22Rik; AW552122; EPI; extrinsic pathway inhibitor; LACI; lipoprotein-associated coagulation inhibitor
Orthologs:
Homo sapiens (human) : TFPI (tissue factor pathway inhibitor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tfpi (tissue factor pathway inhibitor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tfpi (tissue factor pathway inhibitor)
Pan paniscus (bonobo/pygmy chimpanzee) : TFPI (tissue factor pathway inhibitor)
Canis lupus familiaris (dog) : TFPI (tissue factor pathway inhibitor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tfpi (tissue factor pathway inhibitor)
Sus scrofa (pig) : TFPI (tissue factor pathway inhibitor)
Chlorocebus sabaeus (African green monkey) : TFPI (tissue factor pathway inhibitor)
Heterocephalus glaber (naked mole-rat) : Tfpi (tissue factor pathway inhibitor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl284,432,855 - 84,476,775 (-)EnsemblGRCm38mm10GRCm38
GRCm38284,432,855 - 84,476,775 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37284,273,017 - 84,316,932 (-)NCBIGRCm37mm9NCBIm37
MGSCv36284,233,699 - 84,275,013 (-)NCBImm8
Celera286,041,007 - 86,084,914 (-)NCBICelera
Cytogenetic Map2DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tfpi
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62207
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.