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Gene: Pecam1 (platelet/endothelial cell adhesion molecule 1) Mus musculus
Symbol: Pecam1
Name: platelet/endothelial cell adhesion molecule 1
Description: Predicted to have protein homodimerization activity; protein phosphatase binding activity; and transmembrane signaling receptor activity. Involved in several processes, including Rho protein signal transduction; endothelial cell morphogenesis; and positive regulation of tyrosine phosphorylation of STAT protein. Localizes to several cellular components, including cell-cell contact zone; external side of plasma membrane; and smooth muscle contractile fiber. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; extraembryonic component; and genitourinary system. Human ortholog(s) of this gene implicated in coronary artery disease; coronary stenosis; myocardial infarction; neuroblastoma; and psoriatic arthritis. Orthologous to human PECAM1 (platelet and endothelial cell adhesion molecule 1); PARTICIPATES IN malaria pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C85791; Cd31; expressed sequence C85791; MGC102160; Pecam; PECAM-1; PECAM-1/CD31; platelet endothelial cell adhesion molecule
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl11106,654,217 - 106,750,628 (-)EnsemblGRCm38mm10GRCm38
GRCm3811106,654,213 - 106,715,281 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711106,515,532 - 106,576,595 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611106,470,308 - 106,531,371 (-)NCBImm8
Celera11118,385,876 - 118,446,185 (-)NCBICelera
Cytogenetic Map11E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Pecam1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62220
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.