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Gene: Pecam1 (platelet/endothelial cell adhesion molecule 1) Mus musculus
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Symbol: Pecam1
Name: platelet/endothelial cell adhesion molecule 1
Description: Predicted to have protein homodimerization activity; protein phosphatase binding activity; and transmembrane signaling receptor activity. Involved in several processes, including Rho protein signal transduction; endothelial cell morphogenesis; and positive regulation of tyrosine phosphorylation of STAT protein. Localizes to several cellular components, including cell-cell contact zone; external side of plasma membrane; and smooth muscle contractile fiber. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; extraembryonic component; and genitourinary system. Human ortholog(s) of this gene implicated in coronary artery disease; coronary stenosis; myocardial infarction; neuroblastoma; and psoriatic arthritis. Orthologous to human PECAM1 (platelet and endothelial cell adhesion molecule 1); PARTICIPATES IN malaria pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C85791; Cd31; expressed sequence C85791; MGC102160; Pecam; PECAM-1; PECAM-1/CD31; platelet endothelial cell adhesion molecule
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl11106,654,217 - 106,750,628 (-)EnsemblGRCm38mm10GRCm38
GRCm3811106,654,213 - 106,715,281 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711106,515,532 - 106,576,595 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611106,470,308 - 106,531,371 (-)NCBImm8
Celera11118,385,876 - 118,446,185 (-)NCBICelera
Cytogenetic Map11E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Pecam1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62220
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.