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Gene: Hif1a (hypoxia inducible factor 1, alpha subunit) Mus musculus
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Symbol: Hif1a
Name: hypoxia inducible factor 1, alpha subunit
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; E-box binding activity; and histone deacetylase binding activity. Involved in several processes, including animal organ development; negative regulation of apoptotic process; and tube morphogenesis. Localizes to motile cilium and nuclear speck. Used to study glycogen storage disease V and glycogen storage disease VII. Human ortholog(s) of this gene implicated in diabetic retinopathy; lung non-small cell carcinoma; myocardial infarction; prostate cancer; and type 2 diabetes mellitus. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system; lung; and sensory organ. Orthologous to human HIF1A (hypoxia inducible factor 1 subunit alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AA959795; ARNT-interacting protein; bHLHe78; HIF-1-alpha; HIF1-alpha; HIF1alpha; hypoxia-inducible factor 1-alpha; MOP1
Orthologs:
Homo sapiens (human) : HIF1A (hypoxia inducible factor 1 subunit alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hif1a (hypoxia inducible factor 1 subunit alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hif1a (hypoxia inducible factor 1 subunit alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : HIF1A (hypoxia inducible factor 1 subunit alpha)
Canis lupus familiaris (dog) : HIF1A (hypoxia inducible factor 1 subunit alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hif1a (hypoxia inducible factor 1 subunit alpha)
Sus scrofa (pig) : HIF1A (hypoxia inducible factor 1 subunit alpha)
Chlorocebus sabaeus (African green monkey) : HIF1A (hypoxia inducible factor 1 subunit alpha)
Heterocephalus glaber (naked mole-rat) : Hif1a (hypoxia inducible factor 1 subunit alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1273,901,375 - 73,947,530 (+)EnsemblGRCm38mm10GRCm38
GRCm381273,901,324 - 73,947,554 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371275,008,854 - 75,048,517 (+)NCBIGRCm37mm9NCBIm37
MGSCv361274,826,868 - 74,865,729 (+)NCBImm8
Celera1275,021,612 - 75,061,060 (+)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1231.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Phenotype Annotations
References - curated
References - uncurated