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Gene: Slc22a2 (solute carrier family 22 (organic cation transporter), member 2) Mus musculus
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Symbol: Slc22a2
Name: solute carrier family 22 (organic cation transporter), member 2
Description: Exhibits organic cation transmembrane transporter activity. Involved in cation transport. Predicted to localize to basolateral plasma membrane and integral component of plasma membrane. Is expressed in several structures, including metanephros; nasal cavity mucosa; nervous system; placenta; and ureter. Human ortholog(s) of this gene implicated in acute kidney failure. Orthologous to human SLC22A2 (solute carrier family 22 member 2); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; INTERACTS WITH 1,1-dichloroethene; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC18339; Oct2; Orct2; organic cation transporter 2; solute carrier family 22 member 2; solute carrier family 22, member 2
Orthologs:
Homo sapiens (human) : SLC22A2 (solute carrier family 22 member 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Slc22a2 (solute carrier family 22 member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc22a2 (solute carrier family 22 member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC22A2 (solute carrier family 22 member 2)
Canis lupus familiaris (dog) : SLC22A2 (solute carrier family 22 member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc22a2 (solute carrier family 22 member 2)
Sus scrofa (pig) : SLC22A2 (solute carrier family 22 member 2)
Chlorocebus sabaeus (African green monkey) : SLC22A2 (solute carrier family 22 member 2)
Heterocephalus glaber (naked mole-rat) : Slc22a2 (solute carrier family 22 member 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1712,584,132 - 12,628,488 (+)EnsemblGRCm38mm10GRCm38
GRCm381712,584,189 - 12,628,489 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371712,777,055 - 12,821,354 (+)NCBIGRCm37mm9NCBIm37
MGSCv361712,427,547 - 12,471,846 (+)NCBImm8
Celera1712,614,783 - 12,660,660 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.61NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Slc22a2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62229
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.