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Gene: Nt5e (5' nucleotidase, ecto) Mus musculus
Symbol: Nt5e
Name: 5' nucleotidase, ecto
Description: Exhibits 5'-nucleotidase activity. Involved in AMP catabolic process; adenosine biosynthetic process; and negative regulation of inflammatory response. Localizes to plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and musculoskeletal system. Human ortholog(s) of this gene implicated in hereditary arterial and articular multiple calcification syndrome. Orthologous to human NT5E (5'-nucleotidase ecto).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2210401F01Rik; 5'-NT; 5'-nucleotidase; AI447961; CD73; ecto-5'-nucleotidase; eNT; NT; Nt5
Homo sapiens (human) : NT5E (5'-nucleotidase ecto)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nt5e (5' nucleotidase, ecto)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nt5e (5'-nucleotidase ecto)
Pan paniscus (bonobo/pygmy chimpanzee) : NT5E (5'-nucleotidase ecto)
Canis lupus familiaris (dog) : NT5E (5'-nucleotidase ecto)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nt5e (5'-nucleotidase ecto)
Sus scrofa (pig) : NT5E (5'-nucleotidase ecto)
Chlorocebus sabaeus (African green monkey) : NT5E (5'-nucleotidase ecto)
Heterocephalus glaber (naked mole-rat) : Nt5e (5'-nucleotidase ecto)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl988,327,197 - 88,372,092 (+)EnsemblGRCm38mm10GRCm38
GRCm38988,327,609 - 88,372,089 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37988,222,447 - 88,266,927 (+)NCBIGRCm37mm9NCBIm37
MGSCv36988,125,533 - 88,169,982 (+)NCBImm8
Celera985,354,734 - 85,399,137 (+)NCBICelera
Cytogenetic Map9E3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Nt5e
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62249
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.