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Gene: Smc1a (structural maintenance of chromosomes 1A) Mus musculus
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Symbol: Smc1a
Name: structural maintenance of chromosomes 1A
Description: Exhibits chromatin binding activity and mediator complex binding activity. Involved in meiotic cell cycle and stem cell population maintenance. Localizes to meiotic cohesin complex and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 2 and early infantile epileptic encephalopathy. Orthologous to human SMC1A (structural maintenance of chromosomes 1A); PARTICIPATES IN cell cycle pathway, mitotic; INTERACTS WITH 17alpha-ethynylestradiol; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5830426I24Rik; chromosome segregation protein SmcB; KIAA0178; mKIAA0178; Sb1.8; segregation of mitotic chromosomes b; SMC (segregation of mitotic chromosomes 1)-like 1; SMC protein 1A; SMC-1-alpha; SMC-1A; Smc1; Smc1alpha; Smc1l1; Smcb; structural maintenance of chromosomes protein 1A
Orthologs:
Homo sapiens (human) : SMC1A (structural maintenance of chromosomes 1A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Smc1a (structural maintenance of chromosomes 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smc1a (structural maintenance of chromosomes 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : SMC1A (structural maintenance of chromosomes 1A)
Canis lupus familiaris (dog) : SMC1A (structural maintenance of chromosomes 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smc1a (structural maintenance of chromosomes 1A)
Sus scrofa (pig) : SMC1A (structural maintenance of chromosomes 1A)
Chlorocebus sabaeus (African green monkey) : SMC1A (structural maintenance of chromosomes 1A)
Heterocephalus glaber (naked mole-rat) : Smc1a (structural maintenance of chromosomes 1A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 EnsemblX152,016,428 - 152,062,694 (+)EnsemblGRCm38mm10GRCm38
GRCm38X152,016,428 - 152,061,973 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X148,450,971 - 148,496,516 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X147,357,144 - 147,402,683 (+)NCBImm8
CeleraX132,369,172 - 132,413,610 (-)NCBICelera
Cytogenetic MapXF3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Smc1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62283
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.