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Gene: Plcb3 (phospholipase C, beta 3) Mus musculus
Symbol: Plcb3
Name: phospholipase C, beta 3
Description: Predicted to have calmodulin binding activity and phosphatidylinositol phospholipase C activity. Predicted to be involved in several processes, including inositol trisphosphate biosynthetic process; phosphatidylinositol catabolic process; and phosphatidylinositol-mediated signaling. Localizes to the postsynaptic cytosol. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PLCB3 (phospholipase C beta 3); PARTICIPATES IN endothelin signaling pathway; G protein mediated signaling pathway via Galphaq family; protein kinase C (PKC) signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3; KIAA4098; mKIAA4098; phosphoinositide phospholipase C-beta-3; phospholipase C-beta-3; PLC-beta-3
Homo sapiens (human) : PLCB3 (phospholipase C beta 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Plcb3 (phospholipase C beta 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plcb3 (phospholipase C beta 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCB3 (phospholipase C beta 3)
Canis lupus familiaris (dog) : PLCB3 (phospholipase C beta 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plcb3 (phospholipase C beta 3)
Sus scrofa (pig) : PLCB3 (phospholipase C beta 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38196,953,708 - 6,975,006 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37197,028,203 - 7,044,242 (-)NCBIGRCm37mm9NCBIm37
MGSCv36197,020,757 - 7,036,796 (-)NCBImm8
Celera196,730,717 - 6,746,816 (-)NCBICelera
Cytogenetic Map19 ANCBI
cM Map195.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Plcb3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62285
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.