(R)-noradrenaline increases activity ISO RGD:61993 6480464 Norepinephrine results in increased activity of PLCB3 protein CTD PMID:16714034 (R)-noradrenaline multiple interactions ISO RGD:61993 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:16714034 , PMID:19225867 (R)-noradrenaline increases expression ISO RGD:61993 6480464 Norepinephrine results in increased expression of PLCB3 mRNA, Norepinephrine results in increased expression of PLCB3 protein CTD PMID:16714034 , PMID:19225867 1,2-dimethylhydrazine multiple interactions ISO RGD:61993 6480464 [APC protein affects the susceptibility to 1, 2-Dimethylhydrazine] which results in decreased expression of PLCB3 mRNA CTD PMID:27840820 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:61993 6480464 Tetrachlorodibenzodioxin results in decreased expression of PLCB3 mRNA CTD PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of PLCB3 mRNA CTD PMID:21570461 2-ethoxyethanol increases expression ISO RGD:61993 6480464 2-ethoxyethanol results in increased expression of PLCB3 mRNA CTD PMID:19643169 2-methoxyethanol increases expression ISO RGD:61993 6480464 methyl cellosolve results in increased expression of PLCB3 mRNA CTD PMID:19643169 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO RGD:61993 6480464 bisindolylmaleimide I inhibits the reaction [Norepinephrine results in increased expression of PLCB3 mRNA], bisindolylmaleimide I inhibits the reaction [Norepinephrine results in increased expression of PLCB3 protein] CTD PMID:16714034 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in increased expression of PLCB3 mRNA CTD PMID:18648102 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of PLCB3 mRNA CTD PMID:16604517 ammonium chloride affects expression ISO RGD:61993 6480464 Ammonium Chloride affects the expression of PLCB3 mRNA CTD PMID:16483693 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:61993 6480464 pyrazolanthrone inhibits the reaction [Norepinephrine results in increased expression of PLCB3 mRNA] CTD PMID:19225867 antirheumatic drug increases expression ISO RGD:731269 6480464 Antirheumatic Agents results in increased expression of PLCB3 mRNA CTD PMID:24449571 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of PLCB3 mRNA CTD PMID:22228805 bisphenol A affects expression ISO RGD:61993 6480464 bisphenol A affects the expression of PLCB3 mRNA CTD PMID:25181051 bisphenol A increases methylation ISO RGD:61993 6480464 bisphenol A results in increased methylation of PLCB3 gene CTD PMID:28505145 bisphenol F decreases expression ISO RGD:61993 6480464 4, 4'-bisphenol F results in decreased expression of PLCB3 mRNA CTD PMID:26186136 calcitriol increases activity ISO RGD:61993 6480464 Calcitriol results in increased activity of PLCB3 protein CTD PMID:12798493 calcitriol increases response to substance ISO RGD:61993 6480464 PLCB3 protein results in increased susceptibility to Calcitriol CTD PMID:12798493 capsaicin decreases expression ISO RGD:61993 6480464 Capsaicin results in decreased expression of PLCB3 mRNA CTD PMID:20349343 carbon nanotube decreases expression EXP 6480464 Nanotubes, Carbon analog results in decreased expression of PLCB3 mRNA CTD PMID:25554681 cobalt dichloride decreases expression ISO RGD:731269 6480464 cobaltous chloride results in decreased expression of PLCB3 mRNA CTD PMID:19320972 dicrotophos increases expression ISO RGD:731269 6480464 dicrotophos results in increased expression of PLCB3 mRNA CTD PMID:28302478 doxorubicin decreases expression ISO RGD:731269 6480464 Doxorubicin results in decreased expression of PLCB3 mRNA CTD PMID:29803840 enzyme inhibitor multiple interactions ISO RGD:731269 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of PLCB3 protein CTD PMID:23301498 ethanol increases expression ISO RGD:61993 6480464 Ethanol results in increased expression of PLCB3 mRNA CTD PMID:20655511 ethanol increases expression EXP 6480464 Ethanol results in increased expression of PLCB3 mRNA CTD PMID:30319688 fenamidone increases expression EXP 6480464 fenamidone results in increased expression of PLCB3 mRNA CTD PMID:27029645 hypochlorous acid decreases expression EXP 6480464 Hypochlorous Acid results in decreased expression of PLCB3 mRNA CTD PMID:19376150 N-ethyl-N-nitrosourea increases mutagenesis EXP 6480464 Ethylnitrosourea results in increased mutagenesis of PLCB3 mRNA CTD PMID:27776689 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of PLCB3 mRNA CTD PMID:22776087 oxytocin affects localization EXP 6480464 Oxytocin affects the localization of PLCB3 protein CTD PMID:11579162 ozone decreases expression ISO RGD:61993 6480464 Ozone results in decreased expression of PLCB3 mRNA CTD PMID:16330353 paraquat increases expression ISO RGD:61993 6480464 Paraquat results in increased expression of PLCB3 mRNA CTD PMID:18198484 phenylephrine increases expression ISO RGD:61993 6480464 Phenylephrine results in increased expression of PLCB3 mRNA CTD PMID:16714034 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of PLCB3 mRNA CTD PMID:17426115 prazosin multiple interactions ISO RGD:61993 6480464 Prazosin inhibits the reaction [Norepinephrine results in increased expression of and results in increased activity of PLCB3 protein] more ... CTD PMID:16714034 , PMID:19225867 pregnenolone 16alpha-carbonitrile decreases expression ISO RGD:61993 6480464 Pregnenolone Carbonitrile results in decreased expression of PLCB3 mRNA CTD PMID:19162173 resveratrol multiple interactions ISO RGD:731269 6480464 resveratrol inhibits the reaction [15-Hydroxy-11 alpha more ... CTD PMID:18291361 sodium arsenite decreases expression ISO RGD:731269 6480464 sodium arsenite results in decreased expression of PLCB3 mRNA CTD PMID:25879800 Soman increases expression ISO RGD:61993 6480464 Soman results in increased expression of PLCB3 mRNA CTD PMID:19281266 U-73122 multiple interactions ISO RGD:61993 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:16714034 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of PLCB3 mRNA CTD PMID:20546886 valproic acid increases methylation ISO RGD:731269 6480464 Valproic Acid results in increased methylation of PLCB3 gene CTD PMID:29154799
Biological Process G protein-coupled receptor signaling pathway ISO RGD:61993 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 inositol trisphosphate biosynthetic process IBA MGI:MGI:97616 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 inositol trisphosphate biosynthetic process IBA MGI:MGI:97616 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 inositol trisphosphate metabolic process ISO RGD:61993 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 intracellular signal transduction IEA InterPro:IPR001192 , InterPro:IPR001711 2290270 UniProtKB GO_REF:0000002, MGI:MGI:2152098 lipid catabolic process IEA UniProtKB-KW:KW-0442 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 lipid catabolic process IEA InterPro:IPR014815 2290270 UniProtKB GO_REF:0000002, MGI:MGI:2152098 lipid metabolic process IEA InterPro:IPR001711 , InterPro:IPR017946 2290270 UniProtKB GO_REF:0000002, MGI:MGI:2152098 lipid metabolic process IEA UniProtKB-KW:KW-0443 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 phosphatidylinositol catabolic process ISO RGD:61993 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 phosphatidylinositol-mediated signaling IBA PANTHER:PTN000036885 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 phosphatidylinositol-mediated signaling ISO RGD:61993 2290270 MGI GO_REF:0000096, MGI:MGI:4417868 post-Golgi vesicle-mediated transport ISO RGD:61993 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 regulation of systemic arterial blood pressure ISO UniProtKB:Q01970 2290270 (MGI:MGI:3804325, PMID:18468998) MGI MGI:MGI:3804325 , PMID:18468998 release of sequestered calcium ion into cytosol IBA MGI:MGI:97616 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 signal transduction IEA UniProtKB-KW:KW-0807 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 signal transduction IEA InterPro:IPR001711 2290270 UniProtKB GO_REF:0000002, MGI:MGI:2152098 Cellular Component cytosol ISO RGD:61993 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 nucleoplasm ISO UniProtKB:Q01970 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 nucleus IEA UniProtKB-KW:KW-0539 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 postsynaptic cytosol IDA 2290270 (MGI:MGI:3703180, PMID:17298601) SynGO MGI:MGI:3703180 , PMID:17298601 protein-containing complex ISO UniProtKB:Q01970 2290270 (MGI:MGI:3804325, PMID:18468998) MGI MGI:MGI:3804325 , PMID:18468998 sarcolemma ISO RGD:61993 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 Molecular Function calcium ion binding IEA InterPro:IPR014815 , InterPro:IPR016280 2290270 UniProtKB GO_REF:0000002, MGI:MGI:2152098 calmodulin binding ISO UniProtKB:Q01970 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 calmodulin binding IBA PANTHER:PTN002569942 , UniProtKB:Q01970 2290270 (PMID:21873635) GO_Central PMID:21873635 hydrolase activity IEA UniProtKB-KW:KW-0378 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 phosphatidylinositol phospholipase C activity ISO RGD:61993 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 phosphatidylinositol phospholipase C activity IBA MGI:MGI:97613 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 phosphoric diester hydrolase activity IEA InterPro:IPR017946 2290270 UniProtKB GO_REF:0000002, MGI:MGI:2152098
Gene-Chemical Interaction Annotations
