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Gene: Plcb3 (phospholipase C, beta 3) Mus musculus
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Symbol: Plcb3
Name: phospholipase C, beta 3
Description: Predicted to have calmodulin binding activity and phosphatidylinositol phospholipase C activity. Predicted to be involved in several processes, including inositol trisphosphate biosynthetic process; phosphatidylinositol catabolic process; and phosphatidylinositol-mediated signaling. Localizes to the postsynaptic cytosol. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PLCB3 (phospholipase C beta 3); PARTICIPATES IN endothelin signaling pathway; G protein mediated signaling pathway via Galphaq family; protein kinase C (PKC) signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3; KIAA4098; mKIAA4098; phosphoinositide phospholipase C-beta-3; phospholipase C-beta-3; PLC-beta-3
Orthologs:
Homo sapiens (human) : PLCB3 (phospholipase C beta 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Plcb3 (phospholipase C beta 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plcb3 (phospholipase C beta 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCB3 (phospholipase C beta 3)
Canis lupus familiaris (dog) : PLCB3 (phospholipase C beta 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plcb3 (phospholipase C beta 3)
Sus scrofa (pig) : PLCB3 (phospholipase C beta 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38196,953,708 - 6,975,006 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37197,028,203 - 7,044,242 (-)NCBIGRCm37mm9NCBIm37
MGSCv36197,020,757 - 7,036,796 (-)NCBImm8
Celera196,730,717 - 6,746,816 (-)NCBICelera
Cytogenetic Map19 ANCBI
cM Map195.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Plcb3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62285
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.