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Gene: Kcnk3 (potassium channel, subfamily K, member 3) Mus musculus
Symbol: Kcnk3
Name: potassium channel, subfamily K, member 3
Description: Predicted to have S100 protein binding activity; potassium channel activity; and protein C-terminus binding activity. Predicted to be involved in several processes, including cellular response to hypoxia; negative regulation of cytosolic calcium ion concentration; and stabilization of membrane potential. Predicted to localize to integral component of plasma membrane. Is expressed in early conceptus; heart; and secondary oocyte. Human ortholog(s) of this gene implicated in primary pulmonary hypertension. Orthologous to human KCNK3 (potassium two pore domain channel subfamily K member 3); INTERACTS WITH 1,2-dimethylhydrazine; 3-isobutyl-1-methyl-7H-xanthine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: acid-sensitive potassium channel protein TASK-1; cardiac two pore background K(+) channel; cTBAK-1; potassium channel subfamily K member 3; TASK; Task-1; TWIK-related acid-sensitive K(+) channel 1; two pore K(+) channel KT3.1; two pore potassium channel KT3.1
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl530,588,170 - 30,625,271 (+)EnsemblGRCm38mm10GRCm38
GRCm38530,588,170 - 30,625,270 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37530,890,543 - 30,927,643 (+)NCBIGRCm37mm9NCBIm37
MGSCv36530,864,751 - 30,901,851 (+)NCBImm8
Celera528,066,527 - 28,103,716 (+)NCBICelera
Cytogenetic Map5B1NCBI
cM Map516.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kcnk3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62289
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.