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Gene: Nfic (nuclear factor I/C) Mus musculus
Symbol: Nfic
Name: nuclear factor I/C
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; odontogenesis of dentin-containing tooth; and positive regulation of transcription by RNA polymerase II. Predicted to localize to the fibrillar center and nucleoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; retina nuclear layer; and skeletal musculature. Orthologous to human NFIC (nuclear factor I C); PARTICIPATES IN forkhead class A signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110019L22Rik; 1500041O16Rik; AA589446; AI746521; CCAAT-box-binding transcription factor; CTF; NF-I/C; NF1-C; NFI-C; nuclear factor 1 C-type; nuclear factor 1-C2; nuclear factor 1/C; TGGCA-binding protein
Homo sapiens (human) : NFIC (nuclear factor I C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nfic (nuclear factor I/C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfic (nuclear factor I C)
Pan paniscus (bonobo/pygmy chimpanzee) : NFIC (nuclear factor I C)
Canis lupus familiaris (dog) : NFIC (nuclear factor I C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfic (nuclear factor I C)
Sus scrofa (pig) : NFIC (nuclear factor I C)
Chlorocebus sabaeus (African green monkey) : NFIC (nuclear factor I C)
Heterocephalus glaber (naked mole-rat) : Nfic (nuclear factor I C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1081,396,186 - 81,455,635 (-)Ensembl
GRCm381081,396,191 - 81,431,919 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371080,858,936 - 80,889,918 (-)NCBIGRCm37mm9NCBIm37
MGSCv361080,799,320 - 80,830,302 (-)NCBImm8
Celera1082,417,224 - 82,449,357 (-)NCBICelera
Cytogenetic Map10 C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Nfic
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62308
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.