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Gene: Arc (activity regulated cytoskeletal-associated protein) Mus musculus
Symbol: Arc
Name: activity regulated cytoskeletal-associated protein
Description: Predicted to have mRNA binding activity. Involved in several processes, including long-term memory; regulation of postsynaptic neurotransmitter receptor internalization; and regulation of synaptic plasticity. Localizes to dendritic spine; glutamatergic synapse; and membrane raft. Is expressed in several structures, including central nervous system; extraembryonic component; metanephros; pancreas mesenchyme; and retina. Orthologous to human ARC (activity regulated cytoskeleton associated protein); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,2',3,3',6,6'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: activity-regulated cytoskeleton-associated protein; activity-regulated gene 3.1 protein homolog; ARC/ARG3.1; Arc3.1; arg3.1; C86064; mArc
Homo sapiens (human) : ARC (activity regulated cytoskeleton associated protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Arc (activity-regulated cytoskeleton-associated protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arc (activity regulated cytoskeleton associated protein)
Pan paniscus (bonobo/pygmy chimpanzee) : ARC (activity regulated cytoskeleton associated protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arc (activity regulated cytoskeleton associated protein)
Sus scrofa (pig) : ARC (activity regulated cytoskeleton associated protein)
Chlorocebus sabaeus (African green monkey) : ARC (activity regulated cytoskeleton associated protein)
Heterocephalus glaber (naked mole-rat) : Arc (activity regulated cytoskeleton associated protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1574,669,083 - 74,672,570 (-)EnsemblGRCm38mm10GRCm38
GRCm381574,669,081 - 74,672,570 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371574,499,513 - 74,503,000 (-)NCBIGRCm37mm9NCBIm37
MGSCv361574,496,338 - 74,499,825 (-)NCBImm8
Celera1576,173,822 - 76,177,304 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1534.25NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Arc
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62329
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.