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Gene: Htr6 (5-hydroxytryptamine (serotonin) receptor 6) Mus musculus
Symbol: Htr6
Name: 5-hydroxytryptamine (serotonin) receptor 6
CRRD ID: 62336
Description: Predicted to have G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Involved in cerebral cortex cell migration and positive regulation of TOR signaling. Localizes to cilium. Is expressed in cerebral cortex intermediate zone; cerebral cortex subventricular zone; and cortical plate. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human HTR6 (5-hydroxytryptamine receptor 6); PARTICIPATES IN serotonin signaling pathway via receptors engaging G alphas protein family; INTERACTS WITH 1,2-dichloroethane; 3',5'-cyclic AMP; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5-HT-6; 5-HT6; 5-hydroxytryptamine receptor 6; MGC144682; MGC144683; serotonin receptor 6
Homo sapiens (human) : HTR6 (5-hydroxytryptamine receptor 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Htr6 (5-hydroxytryptamine receptor 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Htr6 (5-hydroxytryptamine receptor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : HTR6 (5-hydroxytryptamine receptor 6)
Canis lupus familiaris (dog) : HTR6 (5-hydroxytryptamine receptor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Htr6 (5-hydroxytryptamine receptor 6)
Sus scrofa (pig) : HTR6 (5-hydroxytryptamine receptor 6)
Chlorocebus sabaeus (African green monkey) : HTR6 (5-hydroxytryptamine receptor 6)
Heterocephalus glaber (naked mole-rat) : Htr6 (5-hydroxytryptamine receptor 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm394138,787,017 - 138,802,881 (-)NCBI
GRCm384139,059,706 - 139,075,570 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4139,061,108 - 139,075,570 (-)EnsemblGRCm38mm10GRCm38
MGSCv374138,617,324 - 138,630,704 (-)NCBIGRCm37mm9NCBIm37
MGSCv364138,333,485 - 138,346,865 (-)NCBImm8
Celera4140,846,418 - 140,859,919 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map470.57NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Htr6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62336
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.