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Gene: Ptbp1 (polypyrimidine tract binding protein 1) Mus musculus
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Symbol: Ptbp1
Name: polypyrimidine tract binding protein 1
Description: Exhibits RNA binding activity. Involved in gene expression; negative regulation of neuron differentiation; and regulation of RNA metabolic process. Localizes to nucleus. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system gland; sensory organ; and tooth. Orthologous to human PTBP1 (polypyrimidine tract binding protein 1); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA407203; AL033359; heterogeneous nuclear ribonucleoprotein I; hnRNP I; HNRPI; polypyrimidine tract-binding protein 1; pPTB; Ptb; PTB-1; PTB2; PTB3; PTB4
Orthologs:
Homo sapiens (human) : PTBP1 (polypyrimidine tract binding protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptbp1 (polypyrimidine tract binding protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptbp1 (polypyrimidine tract binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PTBP1 (polypyrimidine tract binding protein 1)
Canis lupus familiaris (dog) : PTBP1 (polypyrimidine tract binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptbp1 (polypyrimidine tract binding protein 1)
Sus scrofa (pig) : PTBP1 (polypyrimidine tract binding protein 1)
Chlorocebus sabaeus (African green monkey) : PTBP1 (polypyrimidine tract binding protein 1)
Heterocephalus glaber (naked mole-rat) : Ptbp1 (polypyrimidine tract binding protein 1)
more info ...
Related Pseudogenes: Gm14451   Gm14452   Gm18773   Gm18815   Gm2639   Gm4900   Gm8424  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1079,854,427 - 79,864,771 (+)EnsemblGRCm38mm10GRCm38
GRCm381079,854,432 - 79,864,435 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371079,317,350 - 79,327,178 (+)NCBIGRCm37mm9NCBIm37
MGSCv361079,257,809 - 79,267,900 (+)NCBImm8
Celera1080,869,418 - 80,879,246 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ptbp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62339
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.