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Gene: Klf6 (Kruppel-like factor 6) Rattus norvegicus
Symbol: Klf6
Name: Kruppel-like factor 6
CRRD ID: 62389
Description: Exhibits DNA-binding transcription factor activity and double-stranded DNA binding activity. Involved in several processes, including cellular response to hydrogen peroxide; cellular response to organonitrogen compound; and positive regulation of transcription by RNA polymerase II. Localizes to nucleus. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human KLF6 (Kruppel like factor 6); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Aa1017; Copeb; core promoter element binding protein; core promoter element-binding protein; CPBP; Krueppel-like factor 6; transcription factor Zf9; Zf9
Homo sapiens (human) : KLF6 (Kruppel like factor 6)  HGNC  Alliance
Mus musculus (house mouse) : Klf6 (Kruppel-like factor 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klf6 (Kruppel like factor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : KLF6 (Kruppel like factor 6)
Canis lupus familiaris (dog) : KLF6 (Kruppel like factor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klf6 (Kruppel like factor 6)
Sus scrofa (pig) : KLF6 (Kruppel like factor 6)
Chlorocebus sabaeus (African green monkey) : KLF6 (Kruppel like factor 6)
Heterocephalus glaber (naked mole-rat) : Klf6 (Kruppel like factor 6)
more info ...
Allele / Splice: Klf6m1Mcwi  
Genetic Models: FHH-Klf6m1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01767,887,939 - 67,945,052 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1767,887,939 - 67,945,037 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01769,616,967 - 69,674,031 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41775,578,498 - 75,585,072 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11775,589,332 - 75,595,905 (-)NCBI
Celera1764,125,707 - 64,134,702 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Klf6
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62389
Created: 2001-04-26
Species: Rattus norvegicus
Last Modified: 2020-09-01
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.