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Gene: Akt3 (thymoma viral proto-oncogene 3) Mus musculus
Symbol: Akt3
Name: thymoma viral proto-oncogene 3
Description: Predicted to have ATP binding activity; protein kinase C binding activity; and protein serine/threonine kinase activity. Involved in several processes, including positive regulation of TOR signaling; positive regulation of cell size; and positive regulation of vasculature development. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in colon cancer; glioblastoma multiforme; prostate adenocarcinoma; prostate cancer; and renal cell carcinoma. Is expressed in several structures, including genitourinary system; musculature; nervous system; retina; and skin. Orthologous to human AKT3 (AKT serine/threonine kinase 3); PARTICIPATES IN altered phosphatidylinositol 3-kinase-Akt signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; sphingosine 1-phosphate signaling pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI851531; D930002M15Rik; Nmf350; PKB gamma; protein kinase Akt-3; protein kinase B gamma; RAC-gamma serine/threonine-protein kinase; RAC-PK-gamma
Homo sapiens (human) : AKT3 (AKT serine/threonine kinase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Akt3 (AKT serine/threonine kinase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akt3 (AKT serine/threonine kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : AKT3 (AKT serine/threonine kinase 3)
Canis lupus familiaris (dog) : AKT3 (AKT serine/threonine kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akt3 (AKT serine/threonine kinase 3)
Sus scrofa (pig) : AKT3 (AKT serine/threonine kinase 3)
Chlorocebus sabaeus (African green monkey) : AKT3 (AKT serine/threonine kinase 3)
Heterocephalus glaber (naked mole-rat) : Akt3 (AKT serine/threonine kinase 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1177,020,073 - 177,258,203 (-)EnsemblGRCm38mm10GRCm38
GRCm381177,020,076 - 177,261,781 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371178,952,246 - 179,178,898 (-)NCBIGRCm37mm9NCBIm37
MGSCv361178,858,791 - 179,085,442 (-)NCBImm8
Celera1184,083,831 - 184,309,489 (-)NCBICelera
Cytogenetic Map1H4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Akt3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62395
Created: 2001-04-26
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.