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Gene: Ffar1 (free fatty acid receptor 1) Rattus norvegicus
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Symbol: Ffar1
Name: free fatty acid receptor 1
Description: Exhibits fatty acid binding activity. Involved in G protein-coupled receptor signaling pathway; positive regulation of calcium ion transport into cytosol; and positive regulation of insulin secretion. Predicted to localize to the integral component of plasma membrane. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human FFAR1 (free fatty acid receptor 1); INTERACTS WITH aldehydo-D-glucose; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: G protein-coupled receptor 40; G-protein coupled receptor 40; Gpr40
Orthologs:
Homo sapiens (human) : FFAR1 (free fatty acid receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Ffar1 (free fatty acid receptor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ffar1 (free fatty acid receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FFAR1 (free fatty acid receptor 1)
Canis lupus familiaris (dog) : FFAR1 (free fatty acid receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ffar1 (free fatty acid receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0189,308,475 - 89,309,379 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0190,463,925 - 90,464,829 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4185,917,624 - 85,918,528NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1185,995,734 - 85,996,639NCBI
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ffar1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 628613
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.