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Gene: Cyp2b3 (cytochrome P450, family 2, subfamily b, polypeptide 3) Rattus norvegicus
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Symbol: Cyp2b3
Name: cytochrome P450, family 2, subfamily b, polypeptide 3
Description: Predicted to have heme binding activity and monooxygenase activity. Involved in response to drug and response to organic cyclic compound. Localizes to the intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human CYP2B6 (cytochrome P450 family 2 subfamily B member 6); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Cyp2b6; CYPIIB3; cytochrome P450 2B3; cytochrome P450 2B3-like; cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6; cytochrome P450IIB3
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0183,163,103 - 83,236,615 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0184,445,481 - 84,491,180 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4181,084,984 - 81,185,251 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1181,486,546 - 81,659,871 (+)NCBI
Celera176,082,604 - 76,158,885 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Cyp2b3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 628627
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.