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Gene: Acox2 (acyl-CoA oxidase 2) Rattus norvegicus
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Symbol: Acox2
Name: acyl-CoA oxidase 2
Description: Exhibits 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Involved in fatty acid beta-oxidation. Localizes to the peroxisome. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 6. Orthologous to human ACOX2 (acyl-CoA oxidase 2); PARTICIPATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis pathway; congenital bile acid synthesis defect pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,4,7,8-Pentachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase; acyl-CoA oxidase 2, branched chain; acyl-Coenzyme A oxidase 2; acyl-Coenzyme A oxidase 2, branched chain; peroxisomal acyl-coenzyme A oxidase 2; THCA-CoA oxidase; THCCox; trihydroxycoprostanoyl-CoA oxidase
Orthologs:
Homo sapiens (human) : ACOX2 (acyl-CoA oxidase 2)  HGNC  Alliance
Mus musculus (house mouse) : Acox2 (acyl-Coenzyme A oxidase 2, branched chain)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acox2 (acyl-CoA oxidase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ACOX2 (acyl-CoA oxidase 2)
Canis lupus familiaris (dog) : ACOX2 (acyl-CoA oxidase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acox2 (acyl-CoA oxidase 2)
Sus scrofa (pig) : ACOX2 (acyl-CoA oxidase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01518,449,304 - 18,481,472 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1518,451,144 - 18,481,470 (+)Ensembl
Rnor_5.01522,418,099 - 22,449,500 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41518,645,349 - 18,677,855 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11518,645,348 - 18,677,855 (+)NCBI
Celera1516,620,632 - 16,652,578 (+)NCBICelera
Cytogenetic Map15p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Acox2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 628684
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.