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Gene: Zc3hav1 (zinc finger CCCH-type containing, antiviral 1) Rattus norvegicus
Symbol: Zc3hav1
Name: zinc finger CCCH-type containing, antiviral 1
CRRD ID: 628694
Description: Exhibits RNA binding activity and identical protein binding activity. Involved in several processes, including negative regulation of viral genome replication; positive regulation of mRNA catabolic process; and regulation of defense response to virus by host. Localizes to cytoplasm and nucleus. Orthologous to human ZC3HAV1 (zinc finger CCCH-type containing, antiviral 1); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; acetamide; ammonium chloride.
Type: protein-coding
Also known as: ADP-ribosyltransferase diphtheria toxin-like 13; ARTD13; CCCH-type zinc finger antiviral protein (Zap); inactive Poly [ADP-ribose] polymerase 13; PARP13; rZAP; Zap; zinc finger antiviral protein; zinc finger CCCH type, antiviral 1; zinc finger CCCH-type antiviral protein 1
Homo sapiens (human) : ZC3HAV1 (zinc finger CCCH-type containing, antiviral 1)  HGNC  Alliance
Mus musculus (house mouse) : Zc3hav1 (zinc finger CCCH type, antiviral 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zc3hav1 (zinc finger CCCH-type containing, antiviral 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ZC3HAV1 (zinc finger CCCH-type containing, antiviral 1)
Canis lupus familiaris (dog) : ZC3HAV1 (zinc finger CCCH-type containing, antiviral 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zc3hav1 (zinc finger CCCH-type containing, antiviral 1)
Sus scrofa (pig) : ZC3HAV1 (zinc finger CCCH-type containing, antiviral 1)
Chlorocebus sabaeus (African green monkey) : ZC3HAV1 (zinc finger CCCH-type containing, antiviral 1)
Heterocephalus glaber (naked mole-rat) : Zc3hav1 (zinc finger CCCH-type containing, antiviral 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0466,012,111 - 66,062,160 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl466,011,915 - 66,062,089 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0465,826,564 - 65,876,469 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4465,854,471 - 65,894,691 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1466,131,238 - 66,170,505 (-)NCBI
Celera462,042,340 - 62,082,577 (-)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Zc3hav1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 628694
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.