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Gene: Snx27 (sorting nexin 27) Rattus norvegicus
Symbol: Snx27
Name: sorting nexin 27
CRRD ID: 628705
Description: Exhibits ionotropic glutamate receptor binding activity and phosphatidylinositol-3-phosphate binding activity. Involved in several processes, including endosome to plasma membrane protein transport; negative regulation of inward rectifier potassium channel activity; and positive regulation of AMPA glutamate receptor clustering. Localizes to several cellular components, including cytosol; early endosome; and postsynaptic density. Predicted to colocalize with WASH complex and retromer complex. Orthologous to human SNX27 (sorting nexin 27); PARTICIPATES IN retromer-mediated pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MAP-responsive gene protein; methamphetamine (MAP) responsive transcript 1; methamphetamine-responsive transcript 1 protein; Mrt1; PDZ protein Mrt1; PDZ-protein Mrt1; sorting nexin family member 27; sorting nexin-27
Homo sapiens (human) : SNX27 (sorting nexin 27)  HGNC  Alliance
Mus musculus (house mouse) : Snx27 (sorting nexin family member 27)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Snx27 (sorting nexin 27)
Pan paniscus (bonobo/pygmy chimpanzee) : SNX27 (sorting nexin 27)
Canis lupus familiaris (dog) : SNX27 (sorting nexin 27)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Snx27 (sorting nexin 27)
Sus scrofa (pig) : SNX27 (sorting nexin 27)
Chlorocebus sabaeus (African green monkey) : SNX27 (sorting nexin 27)
Heterocephalus glaber (naked mole-rat) : Snx27 (sorting nexin 27)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02195,738,613 - 195,821,608 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2195,738,619 - 195,821,608 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02215,217,238 - 215,300,226 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42189,471,254 - 189,554,249 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12189,421,366 - 189,507,587 (-)NCBI
Celera2174,686,309 - 174,766,065 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Snx27
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 628705
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.