Gene: Cd86 (CD86 molecule) Rattus norvegicus
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Symbol: Cd86
Name: CD86 molecule
Description: Exhibits signaling receptor binding activity; involved in several processes, including T cell proliferation involved in immune response, aging, and defense response to other organism; localizes to the cell surface; used to study adult T-cell leukemia and bronchiolitis obliterans; biomarker of asthma, corneal disease, middle cerebral artery infarction, and orchitis; orthologous to human CD86 (CD86 molecule); PARTICIPATES IN allograft rejection pathway; autoimmune thyroiditis pathway; graft-versus-host disease pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; (S)-nicotine; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: B7-2; cd86 antigen; membrane glycoprotein; T-lymphocyte activation antigen CD86
Orthologs:
Homo sapiens (human) : CD86 (CD86 molecule)  HGNC  Alliance
Mus musculus (house mouse) : Cd86 (CD86 antigen)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd86 (CD86 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD86 (CD86 molecule)
Canis lupus familiaris (dog) : CD86 (CD86 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd86 (CD86 molecule)
Sus scrofa (pig) : CD86 (CD86 molecule)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01167,060,305 - 67,117,990 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01170,150,748 - 70,208,995 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41166,215,233 - 66,238,882 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11166,272,821 - 66,296,468 (-)NCBI
Celera1163,635,203 - 63,670,914 (+)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Cd86
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 628714
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.