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Gene: Homer1 (homer scaffold protein 1) Rattus norvegicus
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Symbol: Homer1
Name: homer scaffold protein 1
Description: Exhibits several functions, including protein heterodimerization activity; scaffold protein binding activity; and type 5 metabotropic glutamate receptor binding activity. Involved in several processes, including protein tetramerization; regulation of dendritic spine maintenance; and response to cocaine. Localizes to several cellular components, including the dendritic shaft; glutamatergic synapse; and postsynaptic density. Colocalizes with the excitatory synapse. Orthologous to human HOMER1 (homer scaffold protein 1); PARTICIPATES IN glutamate signaling pathway; INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: homer homolog 1; homer homolog 1 (Drosophila); homer protein homolog 1; homer scaffolding protein 1; homer, neuronal immediate early gene, 1; HOMER1F; PSD-Zip45; scaffold protein; VASP/Ena-related gene up-regulated during seizure and LTP 1; Vesl-1
Orthologs:
Homo sapiens (human) : HOMER1 (homer scaffold protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Homer1 (homer scaffolding protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Homer1 (homer scaffold protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HOMER1 (homer scaffold protein 1)
Canis lupus familiaris (dog) : HOMER1 (homer scaffold protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Homer1 (homer scaffold protein 1)
Sus scrofa (pig) : HOMER1 (homer scaffold protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0222,909,550 - 23,012,303 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0242,106,531 - 42,208,187 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera220,619,882 - 20,720,929 (+)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Homer1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 628725
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.