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Gene: Fkbp4 (FKBP prolyl isomerase 4) Rattus norvegicus
Symbol: Fkbp4
Name: FKBP prolyl isomerase 4
CRRD ID: 628729
Description: Exhibits copper-dependent protein binding activity and tau protein binding activity. Involved in copper ion transport and negative regulation of microtubule polymerization. Localizes to several cellular components, including axonal growth cone; neuronal cell body; and perinuclear region of cytoplasm. Orthologous to human FKBP4 (FKBP prolyl isomerase 4); PARTICIPATES IN aldosterone signaling pathway; cortisol signaling pathway; estrogen signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-nitrofluorene.
Type: protein-coding
Also known as: 52 kDa FK506-binding protein; 52 kDa FKBP; 59 kDa immunophilin; FK506 binding protein 4; FK506 binding protein 4 (59 kDa); FK506 binding protein 52; FK506-binding protein 4; FKBP-4; FKBP-52; FKBP52 protein; FKBP59; HBI; HSP-binding immunophilin; immunophilin FKBP52; p59; peptidyl-prolyl cis-trans isomerase; peptidyl-prolyl cis-trans isomerase FKBP4; PPIase; PPIase FKBP4; rotamase
Homo sapiens (human) : FKBP4 (FKBP prolyl isomerase 4)  HGNC  Alliance
Mus musculus (house mouse) : Fkbp4 (FK506 binding protein 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fkbp4 (FKBP prolyl isomerase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : FKBP4 (FKBP prolyl isomerase 4)
Canis lupus familiaris (dog) : FKBP4 (FKBP prolyl isomerase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fkbp4 (FKBP prolyl isomerase 4)
Sus scrofa (pig) : FKBP4 (FKBP prolyl isomerase 4)
Chlorocebus sabaeus (African green monkey) : FKBP4 (FKBP prolyl isomerase 4)
Heterocephalus glaber (naked mole-rat) : Fkbp4 (FKBP prolyl isomerase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04161,748,993 - 161,757,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4161,748,993 - 161,757,447 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04226,954,534 - 226,962,988 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44165,448,027 - 165,456,481 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14165,694,232 - 165,699,379 (-)NCBI
Celera4150,404,805 - 150,413,259 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Fkbp4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 628729
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.