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Gene: Fkbp4 (FKBP prolyl isomerase 4) Rattus norvegicus
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Symbol: Fkbp4
Name: FKBP prolyl isomerase 4
Description: Exhibits copper-dependent protein binding activity and tau protein binding activity. Involved in copper ion transport and negative regulation of microtubule polymerization. Localizes to several cellular components, including the axonal growth cone; cytoplasm; and neuronal cell body. Orthologous to human FKBP4 (FKBP prolyl isomerase 4); PARTICIPATES IN aldosterone signaling pathway; cortisol signaling pathway; estrogen signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-nitrofluorene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 52 kDa FK506-binding protein; 52 kDa FKBP; 59 kDa immunophilin; FK506 binding protein 4; FK506 binding protein 4 (59 kDa); FK506 binding protein 52; FK506-binding protein 4; FKBP-4; FKBP-52; FKBP52 protein; FKBP59; HBI; HSP-binding immunophilin; immunophilin FKBP52; p59; peptidyl-prolyl cis-trans isomerase; peptidyl-prolyl cis-trans isomerase FKBP4; PPIase; PPIase FKBP4; rotamase
Orthologs:
Homo sapiens (human) : FKBP4 (FKBP prolyl isomerase 4)  HGNC  Alliance
Mus musculus (house mouse) : Fkbp4 (FK506 binding protein 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fkbp4 (FKBP prolyl isomerase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : FKBP4 (FKBP prolyl isomerase 4)
Canis lupus familiaris (dog) : FKBP4 (FKBP prolyl isomerase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fkbp4 (FKBP prolyl isomerase 4)
Sus scrofa (pig) : FKBP4 (FKBP prolyl isomerase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04161,748,993 - 161,757,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04226,954,534 - 226,962,988 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44165,448,027 - 165,456,481 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14165,694,232 - 165,699,379 (-)NCBI
Celera4150,404,805 - 150,413,259 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Fkbp4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 628729
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.