Gene: Duox2 (dual oxidase 2) Rattus norvegicus
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Symbol: Duox2
Name: dual oxidase 2
Description: Predicted to have NAD(P)H oxidase activity, calcium ion binding activity, and superoxide-generating NADPH oxidase activity; predicted to be involved in several processes, including animal organ development, cuticle development, and cytokine-mediated signaling pathway; predicted to localize to several cellular components, including the NADPH oxidase complex, apical part of cell, and cytoplasm; orthologous to human DUOX2 (dual oxidase 2); PARTICIPATES IN thyroid hormone biosynthetic pathway; INTERACTS WITH 3,7-dihydropurine-6-thione; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: large NOX 2; long NOX 2; NADH/NADPH thyroid oxidase THOX2; Thox2; thyroid oxidase 2
Orthologs:
Homo sapiens (human) : DUOX2 (dual oxidase 2)  HGNC  Alliance
Mus musculus (house mouse) : Duox2 (dual oxidase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Duox2 (dual oxidase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DUOX2 (dual oxidase 2)
Canis lupus familiaris (dog) : DUOX2 (dual oxidase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Duox2 (dual oxidase 2)
Sus scrofa (pig) : DUOX2 (dual oxidase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03114,218,187 - 114,237,808 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03120,757,633 - 120,776,304 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43109,059,360 - 109,077,106 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13108,964,932 - 108,982,679 (-)NCBI
Celera3108,124,745 - 108,142,508 (-)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Duox2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 628761
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.