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Gene: Lama3 (laminin subunit alpha 3) Rattus norvegicus
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Symbol: Lama3
Name: laminin subunit alpha 3
Description: Involved in cell-cell adhesion and hemidesmosome assembly. Localizes to the cell-cell adherens junction; hemidesmosome; and laminin-3 complex. Predicted to colocalize with the basement membrane. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa; junctional epidermolysis bullosa Herlitz type; junctional epidermolysis bullosa non-Herlitz type; and lung small cell carcinoma. Orthologous to human LAMA3 (laminin subunit alpha 3); PARTICIPATES IN syndecan signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: laminin 5 alpha 3; laminin subunit alpha-3; laminin, alpha 3; LOC307582; LOW QUALITY PROTEIN: laminin subunit alpha-3; similar to Laminin alpha-3 chain precursor (Nicein alpha subunit)
Orthologs:
Homo sapiens (human) : LAMA3 (laminin subunit alpha 3)  HGNC  Alliance
Mus musculus (house mouse) : Lama3 (laminin, alpha 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lama3 (laminin subunit alpha 3)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100977893 (laminin subunit alpha-3)
Canis lupus familiaris (dog) : LAMA3 (laminin subunit alpha 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lama3 (laminin subunit alpha 3)
Sus scrofa (pig) : LAMA3 (laminin subunit alpha 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0183,704,866 - 3,941,215 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0183,712,673 - 3,939,550 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4184,030,463 - 4,121,355 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1184,030,462 - 4,121,355 (+)NCBI
Celera183,569,544 - 3,806,888 (+)NCBICelera
Cytogenetic Map18p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Lama3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 628776
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.