Gene: Sars (seryl-tRNA synthetase) Rattus norvegicus
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Symbol: Sars
Name: seryl-tRNA synthetase
Description: Predicted to have RNA polymerase II proximal promoter sequence-specific DNA binding activity; protein homodimerization activity; and serine-tRNA ligase activity. Predicted to be involved in several processes, including negative regulation of angiogenesis; negative regulation of vascular endothelial growth factor production; and seryl-tRNA aminoacylation. Predicted to localize to the cytosol. Orthologous to human SARS (seryl-tRNA synthetase); PARTICIPATES IN dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; nonketotic hyperglycinemia pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC72629; Sars1; serine--tRNA ligase; serine--tRNA ligase, cytoplasmic; serRS; seryl-aminoacyl-tRNA synthetase; seryl-aminoacyl-tRNA synthetase 1; seryl-tRNA synthetase, cytoplasmic; seryl-tRNA(Ser/Sec) synthetase
Orthologs:
Homo sapiens (human) : SARS (seryl-tRNA synthetase)  HGNC  Alliance
Mus musculus (house mouse) : Sars (seryl-aminoacyl-tRNA synthetase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sars (seryl-tRNA synthetase)
Pan paniscus (bonobo/pygmy chimpanzee) : SARS (seryl-tRNA synthetase)
Canis lupus familiaris (dog) : SARS (seryl-tRNA synthetase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sars (seryl-tRNA synthetase)
Sus scrofa (pig) : SARS (seryl-tRNA synthetase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02211,219,743 - 211,235,475 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02230,689,709 - 230,705,638 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42203,995,537 - 204,011,262 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12203,960,370 - 203,964,749 (-)NCBI
Celera2188,711,760 - 188,728,010 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Sars
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 628813
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.