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Gene: Itgb5 (integrin subunit beta 5) Rattus norvegicus
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Symbol: Itgb5
Name: integrin subunit beta 5
Description: Exhibits signaling receptor binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; endodermal cell differentiation; and stress fiber assembly. Predicted to localize to several cellular components, including focal adhesion; glutamatergic synapse; and integral component of plasma membrane. Orthologous to human ITGB5 (integrin subunit beta 5); PARTICIPATES IN integrin mediated signaling pathway; arrhythmogenic right ventricular cardiomyopathy pathway; cell-extracellular matrix signaling pathway; INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: integrin beta-5; integrin, beta 5; LOC498091; RGD1563276; similar to integrin beta-5
Orthologs:
Homo sapiens (human) : ITGB5 (integrin subunit beta 5)  HGNC  Alliance
Mus musculus (house mouse) : Itgb5 (integrin beta 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgb5 (integrin subunit beta 5)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGB5 (integrin subunit beta 5)
Canis lupus familiaris (dog) : ITGB5 (integrin subunit beta 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgb5 (integrin subunit beta 5)
Sus scrofa (pig) : ITGB5 (integrin subunit beta 5)
Chlorocebus sabaeus (African green monkey) : ITGB5 (integrin subunit beta 5)
Heterocephalus glaber (naked mole-rat) : Itgb5 (integrin subunit beta 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01170,056,500 - 70,172,164 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1170,056,500 - 70,172,372 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01173,146,146 - 73,261,215 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11168,699,866 - 68,710,334 (+)NCBI
Celera1166,279,067 - 66,394,763 (-)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Itgb5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 628869
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.