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Gene: Eaf2 (ELL associated factor 2) Rattus norvegicus
Symbol: Eaf2
Name: ELL associated factor 2
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of cell growth; negative regulation of epithelial cell proliferation involved in prostate gland development; and positive regulation of transcription by RNA polymerase II. Predicted to localize to transcription elongation factor complex. Orthologous to human EAF2 (ELL associated factor 2); PARTICIPATES IN RNA polymerase II transcription elongation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; acrylamide.
Type: protein-coding
Also known as: ELL-associated factor 2; testosterone regulated apoptosis inducer and tumor suppressor; testosterone-regulated apoptosis inducer and tumor suppressor protein; Traits
Homo sapiens (human) : EAF2 (ELL associated factor 2)  HGNC  Alliance
Mus musculus (house mouse) : Eaf2 (ELL associated factor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Eaf2 (ELL associated factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : EAF2 (ELL associated factor 2)
Canis lupus familiaris (dog) : EAF2 (ELL associated factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Eaf2 (ELL associated factor 2)
Sus scrofa (pig) : EAF2 (ELL associated factor 2)
Chlorocebus sabaeus (African green monkey) : EAF2 (ELL associated factor 2)
Heterocephalus glaber (naked mole-rat) : Eaf2 (ELL associated factor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01166,878,658 - 66,923,092 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,878,658 - 66,923,092 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01169,969,912 - 70,013,412 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41165,763,410 - 65,809,967 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11165,820,998 - 65,867,556 (+)NCBI
Celera1163,432,421 - 63,474,673 (+)NCBICelera
Cytogenetic Map11q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Eaf2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 628879
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.