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Gene: Prrx1 (paired related homeobox 1) Rattus norvegicus
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Symbol: Prrx1
Name: paired related homeobox 1
Description: Predicted to have several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; HMG box domain binding activity; and transcription coactivator activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to localize to the cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in agnathia-otocephaly complex. Orthologous to human PRRX1 (paired related homeobox 1); INTERACTS WITH acrylamide; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: paired mesoderm homeobox 1; paired mesoderm homeobox protein 1; paired-related homeobox protein 1; Pmx1; Prx-1; rHox
Orthologs:
Homo sapiens (human) : PRRX1 (paired related homeobox 1)  HGNC  Alliance
Mus musculus (house mouse) : Prrx1 (paired related homeobox 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prrx1 (paired related homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PRRX1 (paired related homeobox 1)
Canis lupus familiaris (dog) : PRRX1 (paired related homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prrx1 (paired related homeobox 1)
Sus scrofa (pig) : PRRX1 (paired related homeobox 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01381,147,038 - 81,215,559 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01386,039,713 - 86,107,919 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41378,961,648 - 79,028,882 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11378,975,835 - 79,043,069 (-)NCBI
Celera1375,343,320 - 75,409,614 (-)NCBICelera
Cytogenetic Map13q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Prrx1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 628884
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.