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Gene: Whrn (whirlin) Rattus norvegicus
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Symbol: Whrn
Name: whirlin
Description: Exhibits protein domain specific binding activity. Predicted to be involved in several processes, including detection of mechanical stimulus involved in sensory perception of sound; nervous system development; and paranodal junction maintenance. Localizes to several cellular components, including dendritic shaft; stereocilia ankle link; and stereocilium tip. Colocalizes with photoreceptor connecting cilium and photoreceptor inner segment. Human ortholog(s) of this gene implicated in Usher syndrome type 2D; autosomal recessive nonsyndromic deafness 31; and sensorineural hearing loss. Orthologous to human WHRN (whirlin); PARTICIPATES IN auditory mechanotransduction pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CASK-interacting protein CIP98; Cip98; deafness, autosomal recessive 31; Dfnb31
Orthologs:
Homo sapiens (human) : WHRN (whirlin)  HGNC  Alliance
Mus musculus (house mouse) : Whrn (whirlin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Whrn (whirlin)
Pan paniscus (bonobo/pygmy chimpanzee) : WHRN (whirlin)
Canis lupus familiaris (dog) : WHRN (whirlin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Whrn (whirlin)
Sus scrofa (pig) : WHRN (whirlin)
Chlorocebus sabaeus (African green monkey) : WHRN (whirlin)
Heterocephalus glaber (naked mole-rat) : Whrn (whirlin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0579,235,541 - 79,317,206 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl579,234,950 - 79,317,206 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0583,349,720 - 83,431,410 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4580,382,665 - 80,464,817 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1580,387,779 - 80,469,930 (-)NCBI
Celera575,762,917 - 75,845,137 (-)NCBICelera
Cytogenetic Map5q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Whrn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 631330
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.