Gene: Serpinf1 (serpin family F member 1) Rattus norvegicus
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Symbol: Serpinf1
Name: serpin family F member 1
Description: Predicted to have serine-type endopeptidase inhibitor activity; involved in several processes, including aging, animal organ development, and cellular response to lipid; localizes to several cellular components, including the axon hillock, basement membrane, and extracellular space; used to study Alzheimer's disease, middle cerebral artery infarction, and type 2 diabetes mellitus; biomarker of endometriosis, obesity, portal hypertension, retinal disease (multiple), and type 2 diabetes mellitus; orthologous to human SERPINF1 (serpin family F member 1); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alpha-2 antiplasmin; Dmrs91; Pedf; pigment epithelium-derived factor; serine (or cysteine) peptidase inhibitor, clade F, member 1; serine (or cysteine) proteinase inhibitor, clade F), member 1; serine (or cysteine) proteinase inhibitor, clade F, member 1; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; sserpin family F member 1
Orthologs:
Homo sapiens (human) : SERPINF1 (serpin family F member 1)  HGNC  Alliance
Mus musculus (house mouse) : Serpinf1 (serine (or cysteine) peptidase inhibitor, clade F, member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpinf1 (serpin family F member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINF1 (serpin family F member 1)
Canis lupus familiaris (dog) : SERPINF1 (serpin family F member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpinf1 (serpin family F member 1)
Sus scrofa (pig) : SERPINF1 (serpin family F member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01062,241,750 - 62,254,145 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01061,954,919 - 61,969,094 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41062,713,441 - 62,739,444 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11062,727,065 - 62,753,067 (-)NCBI
Celera1059,279,849 - 59,291,539 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Serpinf1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 631369
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.