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Gene: Gpbar1 (G protein-coupled bile acid receptor 1) Rattus norvegicus
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Symbol: Gpbar1
Name: G protein-coupled bile acid receptor 1
Description: Exhibits G protein-coupled receptor activity. Involved in positive regulation of ERK1 and ERK2 cascade and positive regulation of cholangiocyte proliferation. Predicted to localize to the cytoplasm and plasma membrane. Biomarker of polycystic kidney disease. Orthologous to human GPBAR1 (G protein-coupled bile acid receptor 1); INTERACTS WITH ammonium chloride; beta-naphthoflavone; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: G protein-coupled receptor; G-protein coupled bile acid receptor 1; M-BAR; membrane-type receptor for bile acids; Tgr5
Orthologs:
Homo sapiens (human) : GPBAR1 (G protein-coupled bile acid receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Gpbar1 (G protein-coupled bile acid receptor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpbar1 (G protein-coupled bile acid receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GPBAR1 (G protein-coupled bile acid receptor 1)
Canis lupus familiaris (dog) : GPBAR1 (G protein-coupled bile acid receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpbar1 (G protein-coupled bile acid receptor 1)
Sus scrofa (pig) : GPBAR1 (G protein-coupled bile acid receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0981,555,914 - 81,560,931 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl981,559,605 - 81,560,594 (+)Ensembl
Rnor_5.0981,324,651 - 81,327,608 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4973,605,141 - 73,606,130 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1973,752,122 - 73,753,112 (+)NCBI
Celera973,438,636 - 73,439,625 (+)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gpbar1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 631400
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.