Gene: Itgal (integrin subunit alpha L) Rattus norvegicus
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Symbol: Itgal
Name: integrin subunit alpha L
Description: Exhibits protein heterodimerization activity; involved in cell-cell adhesion; localizes to the cell surface; used to study nephritis; orthologous to human ITGAL (integrin subunit alpha L); PARTICIPATES IN integrin mediated signaling pathway; malaria pathway; myocarditis pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: integrin alpha L; integrin alpha-L; integrin, alpha L; LFA-1; lymphocyte function-associated antigen-1
Orthologs:
Homo sapiens (human) : ITGAL (integrin subunit alpha L)  HGNC  Alliance
Mus musculus (house mouse) : Itgal (integrin alpha L)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgal (integrin subunit alpha L)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGAL (integrin subunit alpha L)
Canis lupus familiaris (dog) : ITGAL (integrin subunit alpha L)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgal (integrin subunit alpha L)
Sus scrofa (pig) : ITGAL (integrin subunit alpha L)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01198,744,053 - 198,781,745 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01205,742,280 - 205,780,282 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,561,795 - 186,598,908 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11186,716,379 - 186,726,577 (+)NCBI
Celera1179,569,739 - 179,607,287 (+)NCBICelera
Cytogenetic Map1q37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Itgal
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 631424
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.