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Gene: Itgal (integrin subunit alpha L) Rattus norvegicus
Symbol: Itgal
Name: integrin subunit alpha L
Description: Predicted to have ICAM-3 receptor activity and cell adhesion molecule binding activity. Involved in cell-cell adhesion. Localizes to cell surface. Used to study nephritis. Orthologous to human ITGAL (integrin subunit alpha L); PARTICIPATES IN integrin mediated signaling pathway; malaria pathway; myocarditis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 4,4'-diaminodiphenylmethane; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: integrin alpha L; integrin alpha-L; integrin, alpha L; LFA-1; lymphocyte function-associated antigen-1
Homo sapiens (human) : ITGAL (integrin subunit alpha L)  HGNC  Alliance
Mus musculus (house mouse) : Itgal (integrin alpha L)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgal (integrin subunit alpha L)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGAL (integrin subunit alpha L)
Canis lupus familiaris (dog) : ITGAL (integrin subunit alpha L)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgal (integrin subunit alpha L)
Sus scrofa (pig) : ITGAL (integrin subunit alpha L)
Chlorocebus sabaeus (African green monkey) : ITGAL (integrin subunit alpha L)
Heterocephalus glaber (naked mole-rat) : Itgal (integrin subunit alpha L)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01198,744,053 - 198,781,745 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,744,050 - 198,781,750 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01205,742,280 - 205,780,282 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,561,795 - 186,598,908 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11186,716,379 - 186,726,577 (+)NCBI
Celera1179,569,739 - 179,607,287 (+)NCBICelera
Cytogenetic Map1q37NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Itgal
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 631424
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2020-04-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.