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Gene: Arfgef2 (ADP ribosylation factor guanine nucleotide exchange factor 2) Rattus norvegicus
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Symbol: Arfgef2
Name: ADP ribosylation factor guanine nucleotide exchange factor 2
Description: Exhibits GABA receptor binding activity and myosin binding activity. Involved in exocytosis. Localizes to several cellular components, including the axonemal microtubule; dendritic spine; and trans-Golgi network. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2); INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited); Big2; brefeldin A-inhibited GEP 2; Brefeldin A-inhibited guanine nucleotide-exchange factor 2; brefeldin A-inhibited guanine nucleotide-exchange protein 2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03163,570,435 - 163,656,612 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3163,570,532 - 163,656,626 (+)Ensembl
Rnor_5.03169,732,829 - 169,817,296 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43157,967,942 - 158,051,359 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13157,873,977 - 157,957,394 (+)NCBI
Celera3154,129,988 - 154,212,427 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Arfgef2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 631430
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.