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Gene: LOC100911453 (methylosome protein 50-like) Rattus norvegicus
Symbol: LOC100911453
Name: methylosome protein 50-like
CRRD ID: 6492663
Description: Predicted to have methyl-CpG binding activity. Predicted to be involved in positive regulation of nucleic acid-templated transcription. Predicted to localize to cytosol; methylosome; and nucleus. Orthologous to human WDR77 (WD repeat domain 77).
Type: protein-coding
RefSeq Status: MODEL
Also known as: methylosome protein 50
No known orthologs. homologs ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Note: LOC100911453 appears to be a duplicate placement of Wdr77 (GeneID: 310769) on Rnor_6.0 that is not present on Rn_Celera (Annotation Release 105) and not supported by synteny in mouse and human. Additionally, gene neighbor LOC100911417 appears to be a duplicate placement of Atp5f1 (Gene ID: 171375). BLASTing LOC100911453 XM_003749373.3 and Wdr77 NM_001008771.3 against the rat genome shows best hits to NC_005101.4 on Rnor_6.0 at locations where LOC100911453 and Wdr77 are annotated and to AC_000070.1 on Rn_Celera only at location where Wdr77 is annotated (Annotation Release 105). 2-sequence BLAST of Wdr77 NM_001008771.3 against LOC100911453 XM_003749373.3 shows high sequence identity (99% coverage, 99% identity). BLASTing LOC100911453 underlying component AABR07012780.1 against the rat genome shows best hits to NC_005101.4 on Rnor_6.0 at the location where LOC100911453 is annotated (hitting itself) and the location where Wdr77 is annotated. 2-sequence BLAST of LOC100911453 underlying component AABR07012780.1 against Wdry77 underlying component AABR07012786.1 shows 99% sequence identity across ~14 kb stretch. [25 Mar 2015]
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02208,420,223 - 208,430,276 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2208,420,309 - 208,587,260 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl2208,420,206 - 208,586,356 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02227,841,698 - 227,851,766 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated


Position Markers
QTLs in Region (Rnor_6.0)


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on LOC100911453
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 6492663
Created: 2012-07-05
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.