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Gene: Ifnl1 (interferon, lambda 1) Rattus norvegicus
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Symbol: Ifnl1
Name: interferon, lambda 1
Description: Predicted to have interleukin-28 receptor binding activity. Predicted to be involved in several processes, including defense response to other organism; negative regulation of immune response; and regulation of gene expression. Predicted to localize to extracellular space and interleukin-28 receptor complex. Human ortholog(s) of this gene implicated in cryoglobulinemia; hepatitis C; liver cirrhosis; and thrombocytopenia. Orthologous to human IFNL1 (interferon lambda 1); IFNL2 (interferon lambda 2); and IFNL3 (interferon lambda 3); INTERACTS WITH genistein (ortholog); valproic acid (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: interferon lambda-2-like; interleukin-28A-like; LOC100911249
Orthologs:
Homo sapiens (human) : IFNL1 (interferon lambda 1)  HGNC  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100976419 (interferon lambda-1)
Canis lupus familiaris (dog) : IL29L (interleukin 29-like)
Sus scrofa (pig) : IL29 (interleukin 29 (interferon, lambda 1))
Chlorocebus sabaeus (African green monkey) : IFNL1 (interferon lambda 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0185,252,103 - 85,253,635 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl185,252,103 - 85,253,635 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0186,468,148 - 86,469,680 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ifnl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 6493686
Created: 2012-07-05
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.