Gene: Hsd3b2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2) Rattus norvegicus
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Symbol: Hsd3b2
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
Description: Exhibits 3-beta-hydroxy-delta5-steroid dehydrogenase activity and steroid delta-isomerase activity; involved in several processes, including animal organ development, cellular hormone metabolic process, and negative regulation of iron ion transport; predicted to localize to the intracellular membrane-bounded organelle; biomarker of hyperprolactinemia and hypertension; orthologous to several human genes including HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2); PARTICIPATES IN 11-beta-hydroxylase deficiency pathway; 17-alpha-hydroxylase deficiency pathway; 21-alpha-hydroxylase deficiency pathway; INTERACTS WITH 17alpha-ethynylestradiol; bisphenol A; fenitrothion.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 3 beta-hydroxysteroid dehydrogenase 6; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 4; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type IV; 3-beta-HSD IV; Hsd3b1; Hsd3b2l1; Hsd3b6; Hydroxy-delta-5-steroid dehydrogenase 3 beta- and steroid delta-isomerase; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6; hydroxysteroid dehydrogenase-6 delta<5>-3-beta; hydroxysteroid dehydrogenase-6, delta<5>-3-beta; MGC109236
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02200,712,895 - 200,722,429 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02221,794,088 - 221,803,545 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42193,337,342 - 193,346,799 (-)NCBIRGSC3.4rn4RGSC3.4
Celera2178,571,952 - 178,581,409 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hsd3b2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 67377
Created: 2001-06-01
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.