Gene: Klkb1 (kallikrein B1) Rattus norvegicus
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Symbol: Klkb1
Name: kallikrein B1
Description: Predicted to have serine-type endopeptidase activity; involved in liver regeneration; localizes to the extracellular space; used to study inflammatory bowel disease; biomarker of liver cirrhosis; orthologous to human KLKB1 (kallikrein B1); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; INTERACTS WITH 1,2-dimethylhydrazine; 1,3,5-trinitro-1,3,5-triazinane; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: fletcher factor; kallikrein B, plasma 1; Kalp1; KALP15; kininogenin; Klk3; MGC108748; PK; Plasma kallikrein; plasma prekallikrein; RATKALP15
Orthologs:
Homo sapiens (human) : KLKB1 (kallikrein B1)  HGNC  Alliance
Mus musculus (house mouse) : Klkb1 (kallikrein B, plasma 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klkb1 (kallikrein B1)
Pan paniscus (bonobo/pygmy chimpanzee) : KLKB1 (kallikrein B1)
Canis lupus familiaris (dog) : KLKB1 (kallikrein B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klkb1 (kallikrein B1)
Sus scrofa (pig) : KLKB1 (kallikrein B1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01650,151,127 - 50,175,407 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01649,874,943 - 49,898,364 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41650,248,935 - 50,272,279 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11650,248,906 - 50,272,347 (+)NCBI
Celera1644,949,240 - 44,972,564 (+)NCBICelera
Cytogenetic Map16q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Klkb1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 67382
Created: 2001-06-01
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.