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Gene: Tbp (TATA box binding protein) Rattus norvegicus
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Symbol: Tbp
Name: TATA box binding protein
Description: Exhibits DNA binding activity. Contributes to DNA-binding transcription factor activity. Involved in positive regulation of transcription, DNA-templated and spermatogenesis. Localizes to the transcription factor TFIID complex. Human ortholog(s) of this gene implicated in hereditary ataxia; late onset Parkinson's disease; schizophrenia; spinocerebellar ataxia type 17; and type 1 diabetes mellitus. Orthologous to human TBP (TATA-box binding protein); PARTICIPATES IN cisplatin drug pathway; RNA polymerase I transcription pathway; RNA polymerase II transcription initiation pathway; INTERACTS WITH 2,4-dinitrotoluene; vinclozolin; 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC93994; TATA-box-binding protein; TFIID
Orthologs:
Homo sapiens (human) : TBP (TATA-box binding protein)  HGNC  Alliance
Mus musculus (house mouse) : Tbp (TATA box binding protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbp (TATA-box binding protein)
Pan paniscus (bonobo/pygmy chimpanzee) : TBP (TATA-box binding protein)
Canis lupus familiaris (dog) : TBP (TATA-box binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbp (TATA-box binding protein)
Sus scrofa (pig) : TBP (TATA-box binding protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0157,491,381 - 57,509,335 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0158,419,943 - 58,438,618 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4154,390,756 - 54,407,563 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1154,393,700 - 54,410,507 (+)NCBI
Celera152,668,920 - 52,685,703 (+)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tbp
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 67398
Created: 2001-06-01
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.