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Gene: Vapb (VAMP associated protein B and C) Rattus norvegicus
Symbol: Vapb
Name: VAMP associated protein B and C
Description: Predicted to have several functions, including FFAT motif binding activity; protein dimerization activity; and tubulin binding activity. Predicted to be involved in several processes, including IRE1-mediated unfolded protein response; endoplasmic reticulum-plasma membrane tethering; and regulation of viral process. Predicted to localize to several cellular components, including the Golgi apparatus; endoplasmic reticulum; and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; amyotrophic lateral sclerosis type 8; autosomal dominant adult-onset proximal spinal muscular atrophy; and spinal muscular atrophy. Orthologous to human VAPB (VAMP associated protein B and C); INTERACTS WITH 17beta-estradiol; ammonium chloride; bisphenol A.
Type: protein-coding
Also known as: MGC72459; VAMP (vesicle-associated membrane protein)-associated protein B and C; VAMP-associated protein B; VAMP-B; VAP-B; vesicle-associated membrane protein, associated protein B and C; vesicle-associated membrane protein-associated protein B
Homo sapiens (human) : VAPB (VAMP associated protein B and C)  HGNC  Alliance
Mus musculus (house mouse) : Vapb (vesicle-associated membrane protein, associated protein B and C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vapb (VAMP associated protein B and C)
Pan paniscus (bonobo/pygmy chimpanzee) : VAPB (VAMP associated protein B and C)
Canis lupus familiaris (dog) : VAPB (VAMP associated protein B and C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vapb (VAMP associated protein B and C)
Sus scrofa (pig) : VAPB (VAMP associated protein B and C)
Chlorocebus sabaeus (green monkey) : VAPB (VAMP associated protein B and C)
Heterocephalus glaber (naked mole-rat) : Vapb (VAMP associated protein B and C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03171,832,558 - 171,871,042 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3171,832,500 - 171,868,647 (+)Ensembl
Rnor_5.03177,890,856 - 177,931,543 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43164,632,388 - 164,669,187 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13164,538,238 - 164,576,441 (+)NCBI
Celera3161,718,437 - 161,754,637 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Vapb
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68326
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.