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Gene: Pde1a (phosphodiesterase 1A) Rattus norvegicus
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Symbol: Pde1a
Name: phosphodiesterase 1A
Description: Exhibits calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity. Involved in cGMP catabolic process; regulation of smooth muscle cell apoptotic process; and regulation of smooth muscle cell proliferation. Localizes to the cytoplasm; neuronal cell body; and nucleus. Orthologous to human PDE1A (phosphodiesterase 1A); PARTICIPATES IN protein kinase A (PKA) signaling pathway; calcium/calcium-mediated signaling pathway; purine metabolic pathway; INTERACTS WITH 3',5'-cyclic GMP; 3-chloropropane-1,2-diol; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 3'-RACE clone 8 phosphodiesterase 1A; 3'-RACEclone8phosphodiesterase1A; 3-RACE clone 8 phosphodiesterase 1A; 3-RACEclone8phosphodiesterase1A; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; phosphodiesterase 1A calmodulin-dependent; phosphodiesterase 1A, calmodulin-dependent
Orthologs:
Homo sapiens (human) : PDE1A (phosphodiesterase 1A)  HGNC  Alliance
Mus musculus (house mouse) : Pde1a (phosphodiesterase 1A, calmodulin-dependent)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde1a (phosphodiesterase 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE1A (phosphodiesterase 1A)
Canis lupus familiaris (dog) : PDE1A (phosphodiesterase 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde1a (phosphodiesterase 1A)
Sus scrofa (pig) : PDE1A (phosphodiesterase 1A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0366,803,247 - 67,263,658 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0373,362,390 - 73,443,903 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4362,650,092 - 62,928,487 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1362,546,463 - 62,824,859 (-)NCBI
Celera364,201,583 - 64,477,508 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pde1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68329
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.