Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: S1pr2 (sphingosine-1-phosphate receptor 2) Rattus norvegicus
Analyze
Symbol: S1pr2
Name: sphingosine-1-phosphate receptor 2
Description: Exhibits G protein-coupled receptor activity. Predicted to be involved in several processes, including negative regulation of excitatory postsynaptic potential; positive regulation of establishment of endothelial barrier; and positive regulation of peptidyl-threonine phosphorylation. Predicted to localize to the plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 68. Orthologous to human S1PR2 (sphingosine-1-phosphate receptor 2); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; aldehydo-D-glucose.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AGR16; Edg5; endothelial differentiation G-protein coupled receptor 5; endothelial differentiation, sphingolipid G-protein-coupled receptor, 5; G-protein coupled receptor 13; G-protein coupled receptor H218; Gpcr13; GPCR18; H218; S1P receptor 2; S1P receptor Edg-5; S1P2; snGPCR18; sphingosine 1-phosphate receptor 2; sphingosine 1-phosphate receptor Edg-5
Orthologs:
Homo sapiens (human) : S1PR2 (sphingosine-1-phosphate receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : S1pr2 (sphingosine-1-phosphate receptor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : S1pr2 (sphingosine-1-phosphate receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : S1PR2 (sphingosine-1-phosphate receptor 2)
Canis lupus familiaris (dog) : S1PR2 (sphingosine-1-phosphate receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : S1pr2 (sphingosine-1-phosphate receptor 2)
Sus scrofa (pig) : S1PR2 (sphingosine-1-phosphate receptor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0821,984,914 - 21,995,806 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0822,041,266 - 22,061,702 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4819,989,867 - 20,000,759 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1819,989,866 - 20,000,759 (-)NCBI
Celera820,897,794 - 20,908,686 (-)NCBICelera
Cytogenetic Map8q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on S1pr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68334
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-10-08
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.