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Gene: Por (cytochrome p450 oxidoreductase) Rattus norvegicus
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Symbol: Por
Name: cytochrome p450 oxidoreductase
Description: Exhibits several functions, including coenzyme binding activity; enzyme binding activity; and oxidoreductase activity. Involved in several processes, including cellular response to hormone stimulus; positive regulation of steroid biosynthetic process; and regulation of cartilage development. Localizes to the membrane and mitochondrion. Human ortholog(s) of this gene implicated in Antley-Bixler syndrome and congenital adrenal hyperplasia. Orthologous to human POR (cytochrome p450 oxidoreductase); PARTICIPATES IN aldosterone biosynthetic pathway; cortisol biosynthetic pathway; doxorubicin pharmacokinetics pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,2,4-trimethylbenzene; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CPR; CYPOR; cytochrome P450 reductase; NADPH--cytochrome P450 reductase; P450 (cytochrome) oxidoreductase; P450R
Orthologs:
Homo sapiens (human) : POR (cytochrome p450 oxidoreductase)  HGNC  Alliance
Mus musculus (house mouse) : Por (P450 (cytochrome) oxidoreductase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Por (P450 (cytochrome) oxidoreductase)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100990437 (NADPH--cytochrome P450 reductase)
Canis lupus familiaris (dog) : POR (cytochrome p450 oxidoreductase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101965545 (NADPH--cytochrome P450 reductase)
Sus scrofa (pig) : POR (P450 (cytochrome) oxidoreductase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01223,998,411 - 24,017,063 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01225,995,663 - 26,014,366 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41222,078,629 - 22,097,301 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11222,065,892 - 22,141,603 (-)NCBI
Celera1222,713,689 - 22,732,174 (-)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Por
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68335
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.