Gene: Htt (huntingtin) Rattus norvegicus
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Symbol: Htt
Name: huntingtin
Description: Exhibits signaling receptor binding activity; involved in several processes, including central nervous system development, mRNA transport, and negative regulation of cysteine-type endopeptidase activity; localizes to several cellular components, including the cytoplasm, neuron projection, and neuronal cell body; used to study Huntington's disease; biomarker of transient cerebral ischemia; orthologous to human HTT (huntingtin); PARTICIPATES IN Huntington's disease pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Hd; HD protein homolog; Hdh; huntingtin (Huntington disease); Huntington disease gene homolog; huntington disease protein homolog
Orthologs:
Homo sapiens (human) : HTT (huntingtin)  HGNC  Alliance
Mus musculus (house mouse) : Htt (huntingtin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Htt (huntingtin)
Pan paniscus (bonobo/pygmy chimpanzee) : HTT (huntingtin)
Canis lupus familiaris (dog) : HTT (huntingtin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Htt (huntingtin)
Sus scrofa (pig) : HTT (huntingtin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01481,105,139 - 81,254,637 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01481,793,632 - 81,942,093 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41481,490,322 - 81,636,856 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11481,492,926 - 81,639,072 (-)NCBI
Celera1474,771,910 - 74,919,669 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Htt
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68337
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-05-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.