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Gene: Fads2 (fatty acid desaturase 2) Rattus norvegicus
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Symbol: Fads2
Name: fatty acid desaturase 2
Description: Predicted to have stearoyl-CoA 9-desaturase activity. Predicted to be involved in very long-chain fatty acid biosynthetic process. Predicted to localize to the endoplasmic reticulum membrane. Orthologous to human FADS2 (fatty acid desaturase 2); PARTICIPATES IN alpha-linoleic acid metabolic pathway; linoleic acid metabolic pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; INTERACTS WITH (+)-schisandrin B; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: acyl-CoA 6-desaturase; D6D; delta(6) desaturase; delta(6) fatty acid desaturase; delta-6 desaturase; delta-6 fatty acid desaturase; Fadsd6; fatty acid desaturase 6; MGC93365
Orthologs:
Homo sapiens (human) : FADS2 (fatty acid desaturase 2)  HGNC  Alliance
Mus musculus (house mouse) : Fads2 (fatty acid desaturase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fads2 (fatty acid desaturase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FADS2 (fatty acid desaturase 2)
Canis lupus familiaris (dog) : FADS2 (fatty acid desaturase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fads2 (fatty acid desaturase 2)
Sus scrofa (pig) : FADS2 (fatty acid desaturase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01225,906,582 - 226,152,568 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1226,114,413 - 226,152,524 (-)Ensembl
Rnor_5.01232,857,004 - 232,857,656 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01233,060,345 - 233,097,316 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41212,512,691 - 212,542,622 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11212,671,121 - 212,701,051 (-)NCBI
Celera1204,204,027 - 204,242,387 (-)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Fads2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68339
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.