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Gene: Dpp6 (dipeptidyl peptidase like 6) Rattus norvegicus
Symbol: Dpp6
Name: dipeptidyl peptidase like 6
CRRD ID: 68402
Description: Predicted to have potassium channel regulator activity. Involved in positive regulation of potassium ion transport and positive regulation of protein localization to plasma membrane. Localizes to cell surface; neuronal cell body; and voltage-gated potassium channel complex. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; autosomal dominant non-syndromic intellectual disability 33; and spinal muscular atrophy. Orthologous to human DPP6 (dipeptidyl peptidase like 6); INTERACTS WITH bis(2-ethylhexyl) phthalate; bisphenol A; bromobenzene.
Type: protein-coding
Also known as: dipeptidyl aminopeptidase-like protein 6; dipeptidyl aminopeptidase-related protein; dipeptidyl peptidase IV-like protein; dipeptidyl peptidase VI; dipeptidylpeptidase 6; dipeptidylpeptidase VI; DPP VI; DPPX
Homo sapiens (human) : DPP6 (dipeptidyl peptidase like 6)  HGNC  Alliance
Mus musculus (house mouse) : Dpp6 (dipeptidylpeptidase 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dpp6 (dipeptidyl peptidase like 6)
Pan paniscus (bonobo/pygmy chimpanzee) : DPP6 (dipeptidyl peptidase like 6)
Canis lupus familiaris (dog) : DPP6 (dipeptidyl peptidase like 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dpp6 (dipeptidyl peptidase like 6)
Sus scrofa (pig) : DPP6 (dipeptidyl peptidase like 6)
Chlorocebus sabaeus (African green monkey) : DPP6 (dipeptidyl peptidase like 6)
Heterocephalus glaber (naked mole-rat) : Dpp6 (dipeptidyl peptidase like 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.044,021,021 - 4,943,675 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl44,021,008 - 4,473,307 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.044,060,496 - 4,970,129 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.442,853,479 - 3,565,666 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.142,853,478 - 3,565,666 (-)NCBI
Celera42,039,300 - 2,691,360 (+)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Dpp6
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68402
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.